HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Melatonin receptor type 1B

External ID: CHEMBL1227856

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 17
First Page: 6496
Last Page: 6511
DOI: 10.1016/j.bmc.2010.06.100

Target ChEMBL ID: CHEMBL1946
ChEMBL Target Name: Melatonin receptor 1B
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
5.12861	Ki	=	5128.61	nM
0.03981	Ki	=	39.81	nM
0.33884	Ki	=	338.84	nM
0.01288	Ki	=	12.88	nM
0.34674	Ki	=	346.74	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Melatonin receptor type 1A

External ID: CHEMBL1227855

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 17
First Page: 6496
Last Page: 6511
DOI: 10.1016/j.bmc.2010.06.100

Target ChEMBL ID: CHEMBL1945
ChEMBL Target Name: Melatonin receptor 1A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10.4713	Ki	=	10471.29	nM
0.05495	Ki	=	54.95	nM
3.80189	Ki	=	3801.89	nM
9.333E-4	Ki	=	0.9333	nM
0.35481	Ki	=	354.81	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Melatonin receptor type 1B

External ID: CHEMBL1227859

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 17
First Page: 6496
Last Page: 6511
DOI: 10.1016/j.bmc.2010.06.100

Target ChEMBL ID: CHEMBL1946
ChEMBL Target Name: Melatonin receptor 1B
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
Ratio	=	0.44
Ratio	=	0.22
Ratio	=	0.5
Ratio	=	0.15

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Melatonin receptor type 1A

External ID: CHEMBL1227858

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 17
First Page: 6496
Last Page: 6511
DOI: 10.1016/j.bmc.2010.06.100

Target ChEMBL ID: CHEMBL1945
ChEMBL Target Name: Melatonin receptor 1A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
Ratio	=	0.26
Ratio	=	0.23
Ratio	=	0.22
Ratio	=	0.04

2014-72-4 靶点实验数据