HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Krueppel-like factor 10

External ID: CHEMBL4419303

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3407312
ChEMBL Target Name: Krueppel-like factor 10
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	47.1	%
Inhibition	=	71.8	%
Inhibition	=	37.6	%
Inhibition	=	39.1	%
Inhibition	=	41.1	%
Inhibition	=	75.65	%
Inhibition	=	83.5	%
Inhibition	=	78	%
Inhibition	=	81.5	%
Inhibition	=	35.49	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Krueppel-like factor 10

External ID: CHEMBL4419304

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL3407312
ChEMBL Target Name: Krueppel-like factor 10
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	IC50				Not Determined
10	IC50	=	10000	nM
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
43	IC50	=	43000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Krueppel-like factor 10

External ID: CHEMBL3411252

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2015
Volume: 58
Issue: 3
First Page: 1466
Last Page: 1478
DOI: 10.1021/jm5018187

Target ChEMBL ID: CHEMBL3407312
ChEMBL Target Name: Krueppel-like factor 10
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition	=	47.1	%
Inhibition	=	71.8	%
Inhibition	=	37.6	%
Inhibition	=	39.1	%
Inhibition				Not Active
Inhibition	=	41.1	%
Inhibition	=	75.65	%
Inhibition	=	83.5	%
Inhibition	=	78	%
Inhibition	=	35.49	%
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Krueppel-like factor 10

External ID: CHEMBL3411253

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2015
Volume: 58
Issue: 3
First Page: 1466
Last Page: 1478
DOI: 10.1021/jm5018187

Target ChEMBL ID: CHEMBL3407312
ChEMBL Target Name: Krueppel-like factor 10
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	IC50				Not Determined
43	IC50	=	43000	nM
10	IC50	=	10000	nM
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
40	IC50	=	40000	nM

201284-76-6 靶点实验数据