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20099-89-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Glycogen synthase kinase-3 beta
External ID: CHEMBL1803565
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 12
First Page: 4042
Last Page: 4056
DOI: 10.1021/jm1016279

Target ChEMBL ID: CHEMBL262
ChEMBL Target Name: Glycogen synthase kinase-3 beta
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
50IC50=50000nM
1IC50=1000nM
2.5IC50=2500nM
2.5IC50=2500nM
1IC50=1000nM
0.5IC50=500nM
100IC50=100000nM
10IC50>10000nM
100IC50>100000nM
100IC50>100000nM
1.5IC50=1500nM
1IC50=1000nM
1.5IC50=1500nM
2IC50=2000nM
100IC50>100000nM
100IC50>100000nM
50IC50=50000nM
0.5IC50=500nM
10IC50>10000nM
3IC50=3000nM