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19357-13-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:BMDM
External ID: CHEMBL5588172
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2024
Volume: 67
Issue: 17
First Page: 15311
Last Page: 15327
DOI: 10.1021/acs.jmedchem.4c00909

Target ChEMBL ID: CHEMBL4296525
ChEMBL Target Name: BMDM
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
8.5IC50=8500nM
2.35IC50=2350nM
28.13IC50=28130nM
3.5IC50=3500nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL5588173
Protocol: N/A
Comment: Journal: J Med Chem
Year: 2024
Volume: 67
Issue: 17
First Page: 15311
Last Page: 15327
DOI: 10.1021/acs.jmedchem.4c00909

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
505.6CC50=505600nM
498.3CC50=498300nM
1332CC50=1332000nM