HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Thyrotropin releasing hormone degrading enzyme

External ID: CHEMBL3880465

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3988623
ChEMBL Target Name: Thyrotropin releasing hormone degrading enzyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Relation	Standard Value	Standard Units
Vmax	=	1.64	U/mg
Vmax	=	2.63	U/mg
Vmax	=	0.11	U/mg
Vmax	=	4.43	U/mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Thyrotropin releasing hormone degrading enzyme

External ID: CHEMBL3880466

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL3988623
ChEMBL Target Name: Thyrotropin releasing hormone degrading enzyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
311	Km	=	311000	nM
34	Km	=	34000	nM
15	Km	=	15000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Thyrotropin releasing hormone degrading enzyme

External ID: CHEMBL3880467

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3988623
ChEMBL Target Name: Thyrotropin releasing hormone degrading enzyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Relation	Standard Value	Standard Units
Vmax/Km	=	0.03	U/mg/uM
Vmax/Km	=	0.08	U/mg/uM
Vmax/Km	=	0.04	U/mg/uM
Vmax/Km	=	0.01	U/mg/uM

190836-86-3 靶点实验数据