HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase, inducible

External ID: CHEMBL700496

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 12
First Page: 1901
Last Page: 1905
DOI: 10.1021/jm960785c

Target ChEMBL ID: CHEMBL4481
ChEMBL Target Name: Nitric oxide synthase, inducible
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
2.5	Ki	=	2500	nM
4.2	Ki	=	4200	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase, brain

External ID: CHEMBL880847

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 12
First Page: 1901
Last Page: 1905
DOI: 10.1021/jm960785c

Target ChEMBL ID: CHEMBL3568
ChEMBL Target Name: Nitric-oxide synthase, brain
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.8	Ki	=	800	nM
0.14	Ki	=	140	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide sythases; iNOS & nNOS

External ID: CHEMBL851192

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 12
First Page: 1901
Last Page: 1905
DOI: 10.1021/jm960785c

Target ChEMBL ID: CHEMBL2096621
ChEMBL Target Name: Nitric oxide sythases; iNOS & nNOS
ChEMBL Target Type: SELECTIVITY GROUP - Target is a pair of proteins for which the selectivity has been assessed
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value
Selectivity index	=	115
Selectivity index	=	7.4

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase, endothelial

External ID: CHEMBL678090

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 12
First Page: 1901
Last Page: 1905
DOI: 10.1021/jm960785c

Target ChEMBL ID: CHEMBL4803
ChEMBL Target Name: Nitric-oxide synthase, endothelial
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
16	Ki	=	16000	nM
0.9	Ki	=	900	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric-oxide synthase (endothelial and brain)

External ID: CHEMBL851191

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 12
First Page: 1901
Last Page: 1905
DOI: 10.1021/jm960785c

Target ChEMBL ID: CHEMBL2111405
ChEMBL Target Name: Nitric-oxide synthase (endothelial and brain)
ChEMBL Target Type: SELECTIVITY GROUP - Target is a pair of proteins for which the selectivity has been assessed
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value
Selectivity index	=	29
Selectivity index	=	7.9

189869-87-2 靶点实验数据