HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL1034618

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2009
Volume: 72
Issue: 4
First Page: 650
Last Page: 655
DOI: 10.1021/np800716f

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
6.3	IC50	=	6300	nM
1.4	IC50	=	1400	nM
5.8	IC50	=	5800	nM
1.6	IC50	=	1600	nM
3.8	IC50	=	3800	nM
5.3	IC50	=	5300	nM
3.9	IC50	=	3900	nM
3.4	IC50	=	3400	nM
3.1	IC50	=	3100	nM
10	IC50	>	10000	nM
5	IC50	=	5000	nM
3.8	IC50	=	3800	nM
1.9	IC50	=	1900	nM
2.2	IC50	=	2200	nM
3.9	IC50	=	3900	nM
0.027	IC50	=	27	nM
1.6	IC50	=	1600	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5577318

Protocol: N/A

Comment: Journal: Bioorg Med Chem
Year: 2024
Volume: 110
First Page: 117793
Last Page: 117793
DOI: 10.1016/j.bmc.2024.117793

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	41.6	%
Inhibition	=	49.4	%
Inhibition	=	79.3	%
Inhibition	=	21.2	%
Inhibition	=	32.9	%
Inhibition	=	73.1	%
Inhibition	=	26.4	%
Inhibition	=	30.2	%
Inhibition	=	55.4	%
Inhibition	=	27.1	%
Inhibition	=	34.3	%
Inhibition	=	74.3	%
Inhibition	=	20.5	%
Inhibition	=	28.7	%
Inhibition	=	51.8	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HCT-8

External ID: CHEMBL1034616

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2009
Volume: 72
Issue: 4
First Page: 650
Last Page: 655
DOI: 10.1021/np800716f

Target ChEMBL ID: CHEMBL613510
ChEMBL Target Name: HCT-8
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
9.7	IC50	=	9700	nM
10	IC50	>	10000	nM
1	IC50	=	1000	nM
10	IC50	>	10000	nM
2.6	IC50	=	2600	nM
6.6	IC50	=	6600	nM
10	IC50	>	10000	nM
9.7	IC50	=	9700	nM
10	IC50	>	10000	nM
8.2	IC50	=	8200	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
4.5	IC50	=	4500	nM
2.5	IC50	=	2500	nM
1.5	IC50	=	1500	nM
6.2	IC50	=	6200	nM
0.037	IC50	=	37	nM
1.8	IC50	=	1800	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bel-7402

External ID: CHEMBL1034617

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2009
Volume: 72
Issue: 4
First Page: 650
Last Page: 655
DOI: 10.1021/np800716f

Target ChEMBL ID: CHEMBL614279
ChEMBL Target Name: Bel-7402
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
8.5	IC50	=	8500	nM
10	IC50	>	10000	nM
1.7	IC50	=	1700	nM
10	IC50	>	10000	nM
4.4	IC50	=	4400	nM
7.5	IC50	=	7500	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
7.6	IC50	=	7600	nM
9.9	IC50	=	9900	nM
10	IC50	>	10000	nM
7.1	IC50	=	7100	nM
9.7	IC50	=	9700	nM
4	IC50	=	4000	nM
2.3	IC50	=	2300	nM
10	IC50	>	10000	nM
0.095	IC50	=	95	nM
6.1	IC50	=	6100	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL1034615

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2009
Volume: 72
Issue: 4
First Page: 650
Last Page: 655
DOI: 10.1021/np800716f

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
2.9	IC50	=	2900	nM
10	IC50	>	10000	nM
3	IC50	=	3000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
7.4	IC50	=	7400	nM
7	IC50	=	7000	nM
10	IC50	>	10000	nM
0.0052	IC50	=	5.2	nM
3.7	IC50	=	3700	nM

18296-45-2 靶点实验数据