HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium falciparum

External ID: CHEMBL4888487

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: MMV Malaria Hit Generation Library

Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
Inhibition	=	15	%
Inhibition	=	-11	%	Outside typical range
Inhibition	=	-11	%	Outside typical range
Inhibition	=	-9	%
Inhibition	=	-18	%	Outside typical range
Inhibition	=	12	%
Inhibition	=	-7	%
Inhibition	=	13	%
Inhibition	=	12	%
Inhibition	=	13	%
Inhibition	=	-15	%	Outside typical range
Inhibition	=	7	%
Inhibition	=	-17	%	Outside typical range
Inhibition	=	-22	%	Outside typical range
Inhibition	=	6	%
Inhibition	=	10	%
Inhibition	=	11	%
Inhibition	=	14	%
Inhibition	=	9	%
Inhibition	=	-15	%	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium falciparum

External ID: CHEMBL4888485

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: MMV Malaria Hit Generation Library

Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
Z score	=	1.23
Inhibition	=	-8	%
Z score	=	1.2
Inhibition	=	-11	%	Outside typical range
Z score	=	-0.08
Inhibition	=	1	%
Z score	=	2.72
Inhibition	=	-24	%	Outside typical range
Z score	=	0.82
Inhibition	=	-5	%
Z score	=	1.48
Inhibition	=	-12	%	Outside typical range
Z score	=	-10.93
Inhibition	=	57	%
Z score	=	-0.31
Inhibition	=	2	%
Z score	=	1.21
Inhibition	=	-8	%
Z score	=	-1.25
Inhibition	=	7	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HepG2

External ID: CHEMBL4888492

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL395
ChEMBL Target Name: HepG2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: MMV Malaria Hit Generation Library

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
4.79	IC50	=	4790	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium falciparum

External ID: CHEMBL4888491

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: MMV Malaria Hit Generation Library

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
5.13	IC50	=	5130	nM
8.51	IC50	=	8510	nM
2.69	IC50	=	2690	nM
10	IC50	>	10000	nM
6.76	IC50	=	6760	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
9.55	IC50	=	9550	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
0.417	IC50	=	417	nM
8.91	IC50	=	8910	nM
10	IC50	>	10000	nM
1.74	IC50	=	1740	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM
0.776	IC50	=	776	nM
7.24	IC50	=	7240	nM

1788674-01-0 靶点实验数据