HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL849082

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Standard Type	Standard Relation	Standard Value
Ratio	=	46

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nucleic Acid

External ID: CHEMBL665656

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Target ChEMBL ID: CHEMBL345
ChEMBL Target Name: Nucleic Acid
ChEMBL Target Type: NUCLEIC-ACID - Target is DNA, RNA or PNA
Relationship Type: M - Molecular target other than protein assigned
Confidence: Target assigned is molecular non-protein target

Standard Type	Standard Relation	Standard Value	Standard Units
DNA binding	=	4.55	M-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL734754

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
ILS	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：P388

External ID: CHEMBL753288

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Target ChEMBL ID: CHEMBL389
ChEMBL Target Name: P388
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.06	IC50	=	60	nM
0.01	IC50	=	10	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL737610

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
OD	=	20	mg kg-1
OD	=	5.9	mg kg-1
OD	=	30	mg kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：CHO-AA8

External ID: CHEMBL618448

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 25
First Page: 4338
Last Page: 4345
DOI: 10.1021/jm00051a010

Target ChEMBL ID: CHEMBL614555
ChEMBL Target Name: CHO-AA8
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.5	IC50	=	1500	nM

178481-68-0 靶点实验数据