HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Glycogen phosphorylase, muscle form

External ID: CHEMBL1817502

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2011
Volume: 19
Issue: 16
First Page: 4746
Last Page: 4771
DOI: 10.1016/j.bmc.2011.06.086

Target ChEMBL ID: CHEMBL4696
ChEMBL Target Name: Glycogen phosphorylase, muscle form
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
16.5	IC50	=	16500	nM
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prostaglandin G/H synthase 1

External ID: CHEMBL762791

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 2
First Page: 434
Last Page: 437
DOI: 10.1021/jm00385a031

Target ChEMBL ID: CHEMBL2094253
ChEMBL Target Name: Cyclooxygenase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Control	=	11	%
Control	=	78	%
Control	=	64	%
Control	=	79	%
Control	=	67	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Glycogen phosphorylase, muscle form

External ID: CHEMBL1817501

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2011
Volume: 19
Issue: 16
First Page: 4746
Last Page: 4771
DOI: 10.1016/j.bmc.2011.06.086

Target ChEMBL ID: CHEMBL4696
ChEMBL Target Name: Glycogen phosphorylase, muscle form
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	28	%
Inhibition	=	24	%
Inhibition	=	3	%
Inhibition	=	8	%
Inhibition	=	22	%
Inhibition	=	1	%
Inhibition	=	49	%
Inhibition	=	32	%
Inhibition	=	18	%
Inhibition	=	60	%
Inhibition	=	11	%
Inhibition	=	30	%
Inhibition	=	24	%
Inhibition	=	38	%
Inhibition	=	27	%
Inhibition	=	32	%
Inhibition	=	25	%
Inhibition	=	40	%
Inhibition	=	24	%
Inhibition	=	26	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL762789

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 2
First Page: 434
Last Page: 437
DOI: 10.1021/jm00385a031

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
230	IC50	=	230000	nM	Outside typical range
240	IC50	=	240000	nM	Outside typical range
150	IC50	=	150000	nM	Outside typical range
290	IC50	=	290000	nM	Outside typical range
190	IC50	=	190000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prostaglandin G/H synthase 1

External ID: CHEMBL762794

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 2
First Page: 434
Last Page: 437
DOI: 10.1021/jm00385a031

Target ChEMBL ID: CHEMBL2094253
ChEMBL Target Name: Cyclooxygenase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Control	=	0	%
Control	=	67	%
Control	=	48	%
Control	=	26	%
Control	=	97	%
Control	=	86	%
Control	=	25	%

17722-20-2 靶点实验数据