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175698-06-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL734235
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 9
First Page: 1898
Last Page: 1906
DOI: 10.1021/jm9600196

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
TD50=307mg kg-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Gamma-aminobutyric acid receptor subunit alpha-3
External ID: CHEMBL681239
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 9
First Page: 1898
Last Page: 1906
DOI: 10.1021/jm9600196

Target ChEMBL ID: CHEMBL1907607
ChEMBL Target Name: GABA-A receptor; anion channel
ChEMBL Target Type: PROTEIN COMPLEX GROUP - Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor)
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
440IC50=440000nMOutside typical range
215000IC50=215000000nMOutside typical range
330IC50=330000nMOutside typical range
2620IC50=2620000nMOutside typical range
2440IC50=2440000nMOutside typical range
3260IC50=3260000nMOutside typical range
850IC50=850000nMOutside typical range
12100IC50=12100000nMOutside typical range
32400IC50=32400000nMOutside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL724390
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 9
First Page: 1898
Last Page: 1906
DOI: 10.1021/jm9600196

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
ED50>600mg.kg-1Outside typical range
ED50=535mg.kg-1Outside typical range
ED50=357mg.kg-1
ED50>750mg.kg-1Outside typical range
ED50=220mg.kg-1
ED50=112mg.kg-1
ED50=41mg.kg-1
ED50=55mg.kg-1
ED50=174mg.kg-1
ED50>600mg.kg-1Outside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL724391
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 9
First Page: 1898
Last Page: 1906
DOI: 10.1021/jm9600196

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
ED50=22mg.kg-1
ED50>900mg.kg-1Outside typical range
ED50=133mg.kg-1
ED50=161mg.kg-1
ED50=128mg.kg-1
ED50>750mg.kg-1Outside typical range
ED50=226mg.kg-1
ED50>900mg.kg-1Outside typical range
ED50=118mg.kg-1
ED50=68mg.kg-1
ED50=71mg.kg-1
ED50=63mg.kg-1
ED50=238mg.kg-1
ED50=46mg.kg-1
ED50>600mg.kg-1Outside typical range