HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL2150289

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 13
First Page: 4815
Last Page: 4830
DOI: 10.1021/jm2004305

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	10	mg.kg-1
ED50	=	74	mg.kg-1
ED50	>	70	mg.kg-1
ED50	>	71	mg.kg-1
ED50	=	120	mg.kg-1
ED50	>	120	mg.kg-1
ED50	>	210	mg.kg-1
ED50	>	62	mg.kg-1
ED50	>	62	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL2150294

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 13
First Page: 4815
Last Page: 4830
DOI: 10.1021/jm2004305

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
TD50	=	19	mg kg-1
TD50	=	47	mg kg-1
TD50	=	63	mg kg-1
TD50				Not Determined
TD50				Not Determined
TD50				Not Determined
TD50				Not Determined
TD50	>	110	mg kg-1
TD50	>	110	mg kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL2150284

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 13
First Page: 4815
Last Page: 4830
DOI: 10.1021/jm2004305

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	15	mg.kg-1
ED50	=	20	mg.kg-1
ED50	=	120	mg.kg-1
ED50	>	22	mg.kg-1
ED50	=	71	mg.kg-1
ED50	>	22	mg.kg-1
ED50	=	100	mg.kg-1
ED50	>	62	mg.kg-1
ED50	>	62	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL2150287

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 13
First Page: 4815
Last Page: 4830
DOI: 10.1021/jm2004305

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
ED50	=	3.3	mg.kg-1
MED	=	16	mg kg-1
ED50	=	64	mg.kg-1
ED50	=	13	mg.kg-1
ED50	=	73	mg.kg-1
MED	=	46	mg kg-1
ED50	>	37	mg.kg-1
ED50				Not Determined
ED50	>	62	mg.kg-1

175481-31-9 靶点实验数据