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17522-04-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Estrogen receptor beta
External ID: CHEMBL679678
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 22
First Page: 3659
Last Page: 3669
DOI: 10.1021/jm9703294

Target ChEMBL ID: CHEMBL2093866
ChEMBL Target Name: Estrogen receptor
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned
Standard TypeStandard RelationStandard ValueStandard Units
Ka=3700000000M-1
Ka=18000000M-1
Ka=1520000000M-1
Ka=2850000000M-1
Ka<1850000M-1
Ka=614000000M-1
Ka=821000000M-1
Ka=70000000M-1
Ka=1090000000M-1
Ka=2930000000M-1
Ka=807000000M-1
Ka=3700000M-1
Ka=2600000000M-1
Ka=88800000M-1
Ka=211000000M-1
Ka=2970000000M-1
Ka=410000000M-1
Ka=62200000M-1
Ka=21500000M-1
Ka=63000000M-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:MCF7
External ID: CHEMBL710197
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 22
First Page: 3659
Last Page: 3669
DOI: 10.1021/jm9703294

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
1.54E-6EC50=0.00154nMOutside typical range
4.19E-6EC50=0.00419nMOutside typical range
0.00141EC50=1.41nM
9.9E-5EC50=0.099nM
5.71E-5EC50=0.0571nM
3.38E-6EC50=0.00338nMOutside typical range
1.18E-4EC50=0.118nM
3.82E-4EC50=0.382nM
0.0335EC50=33.5nM
0.0604EC50=60.4nM
0.00897EC50=8.97nM
3.3E-5EC50=0.033nM
0.0342EC50=34.2nM
0.0284EC50=28.4nM
1.6E-5EC50=0.016nM
3.16E-4EC50=0.316nM
0.00159EC50=1.59nM
0.00167EC50=1.67nM
0.00216EC50=2.16nM
3.65E-5EC50=0.0365nM