HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3881281

Protocol: N/A

Comment: Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Text Value
solubility	Soluble
solubility	Soluble
solubility	Insoluble
solubility	Soluble
solubility	Soluble
solubility	Insoluble
solubility	Insoluble
solubility	Insoluble
solubility	Soluble
solubility	Soluble

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3881261

Protocol: N/A

Comment: Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Relation	Standard Value
LogP	=	1.66
LogP	=	1.67
LogP	=	-0.11
LogP	=	0.66
LogP	=	2.22
LogP	=	1.87
LogP	=	2.6
LogP	=	3.77
LogP	=	2.8
LogP	=	0.05
LogP	=	1.59
LogP	=	2.77
LogP	=	2.67
LogP	=	0.58
LogP	=	1.08
LogP	=	0.32
LogP	=	2.25
LogP	=	3.51
LogP	=	1.01
LogP	=	1.6

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bacteriophytochrome heme oxygenase

External ID: CHEMBL3881262

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3988622
ChEMBL Target Name: Biliverdin-producing heme oxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
15.6	Kd	=	15600	nM
28.8	Kd	=	28800	nM
238.7	Kd	=	238700	nM		Outside typical range
	Kd				Active
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Active
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Biliverdin-producing heme oxygenase

External ID: CHEMBL3881263

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1075209
ChEMBL Target Name: Heme oxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
20.1	Kd	=	20100	nM
28.8	Kd	=	28800	nM
	Kd				Not Determined
	Kd				Active
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Active
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined
	Kd				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL3881279

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: SureChEMBL Patent Bioactivity Data

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC50				Not Determined
MIC50	>	1000	ug.mL-1
MIC50	>	160	ug.mL-1
MIC50				Not Determined
MIC50				Not Determined
MIC50				Not Determined
MIC50	>	1000	ug.mL-1
MIC50	>	1000	ug.mL-1
MIC50	>	1000	ug.mL-1
MIC50				Not Determined
MIC50	>	1000	ug.mL-1
MIC50				Not Determined
MIC50				Not Determined
MIC50	>	1000	ug.mL-1
MIC50	>	1000	ug.mL-1
MIC50				Not Determined
MIC50				Not Determined
MIC50				Not Determined
MIC50				Not Determined
MIC50	>	250	ug.mL-1

175137-25-4 靶点实验数据