HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Solute carrier family 22 member 20

External ID: CHEMBL1008236

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Biol Chem
Year: 2007
Volume: 282
Issue: 33
First Page: 23841
Last Page: 23853
DOI: 10.1074/jbc.m703467200

Target ChEMBL ID: CHEMBL5269
ChEMBL Target Name: Solute carrier family 22 member 20
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
44	Ki	=	44000	nM
309.03	Ki	=	309029.54	nM	Outside typical range
312	Ki	=	312000	nM	Outside typical range
446.684	Ki	=	446683.59	nM	Outside typical range
446	Ki	=	446000	nM	Outside typical range
1.12202	Ki	=	1122.02	nM
1.1	Ki	=	1100	nM
13.8038	Ki	=	13803.84	nM
13.8	Ki	=	13800	nM
9.12011	Ki	=	9120.11	nM
9	Ki	=	9000	nM
81.2831	Ki	=	81283.05	nM
82	Ki	=	82000	nM
281.838	Ki	=	281838.29	nM	Outside typical range
279	Ki	=	279000	nM	Outside typical range
18.197	Ki	=	18197.01	nM
18	Ki	=	18000	nM
8.51138	Ki	=	8511.38	nM
8.4	Ki	=	8400	nM
100	Ki	=	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1008238

Protocol: N/A

Comment: Journal: J Biol Chem
Year: 2007
Volume: 282
Issue: 33
First Page: 23841
Last Page: 23853
DOI: 10.1074/jbc.m703467200

Standard Type	Standard Relation	Standard Value
Ratio pKi	=	0.83
Ratio pKi	=	0.52
Ratio pKi	=	-0.75
Ratio pKi	=	-1.68
Ratio pKi	=	0.62
Ratio pKi	=	1.26
Ratio pKi	=	0.62
Ratio pKi	=	1.63
Ratio pKi	=	1.47
Ratio pKi	=	-0.73
Ratio pKi	=	-0.12
Ratio pKi	=	-1.53
Ratio pKi	=	-0.14
Ratio pKi	=	0.31
Ratio pKi	=	-3.58
Ratio pKi	=	-1.69
Ratio pKi	=	0
Ratio pKi	=	0.55
Ratio pKi	<	-1.71
Ratio pKi	=	1.86

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Solute carrier family 22 member 6

External ID: CHEMBL1008237

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Biol Chem
Year: 2007
Volume: 282
Issue: 33
First Page: 23841
Last Page: 23853
DOI: 10.1074/jbc.m703467200

Target ChEMBL ID: CHEMBL5653
ChEMBL Target Name: Solute carrier family 22 member 6
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
145	Ki	=	145000	nM	Outside typical range
56.2341	Ki	=	56234.13	nM
55.6	Ki	=	55600	nM
9.33254	Ki	=	9332.54	nM
9.4	Ki	=	9400	nM
4.67735	Ki	=	4677.35	nM
4.7	Ki	=	4700	nM
251.189	Ki	=	251188.64	nM	Outside typical range
253	Ki	=	253000	nM	Outside typical range
37.1535	Ki	=	37153.52	nM
38	Ki	=	38000	nM
3467.37	Ki	=	3467368.5	nM	Outside typical range
3500	Ki	=	3500000	nM	Outside typical range
8128.31	Ki	=	8128305.16	nM	Outside typical range
8180	Ki	=	8180000	nM	Outside typical range
3.38844	Ki	=	3388.44	nM
3.4	Ki	=	3400	nM
6.30957	Ki	=	6309.57	nM
6.4	Ki	=	6400	nM
2.95121	Ki	=	2951.21	nM

1730-91-2 靶点实验数据