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150809-45-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HT-29
External ID: CHEMBL3737449
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=65%
Activity=24%
Activity=100%
Activity=100%
Activity=46%
Activity=60%
Activity=100%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HEK293
External ID: CHEMBL3737325
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL614818
ChEMBL Target Name: HEK293
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
IC50=7.1ug.mL-1
IC50=11.4ug.mL-1
IC50=1.2ug.mL-1
IC50=24ug.mL-1
IC50=18ug.mL-1
IC50=84ug.mL-1Outside typical range
IC50=1.1ug.mL-1
IC50=20ug.mL-1
IC50=41ug.mL-1
IC50=0.012ug.mL-1
IC50=3.9ug.mL-1
IC50=19ug.mL-1
IC50=1.3ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:MCF7
External ID: CHEMBL3737324
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
IC50=16.1ug.mL-1
IC50=16ug.mL-1
IC50=6.8ug.mL-1
IC50=21ug.mL-1
IC50=52ug.mL-1Outside typical range
IC50=14ug.mL-1
IC50=23ug.mL-1
IC50=18ug.mL-1
IC50=19ug.mL-1
IC50=0.0021ug.mL-1
IC50=11.3ug.mL-1
IC50=13ug.mL-1
IC50=1.4ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HT-29
External ID: CHEMBL3737323
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
IC50=34.1ug.mL-1
IC50=4.4ug.mL-1
IC50>100ug.mL-1Outside typical range
IC50=26ug.mL-1
IC50=16.1ug.mL-1
IC50=12.9ug.mL-1
IC50=6.9ug.mL-1
IC50=26ug.mL-1
IC50=24ug.mL-1
IC50=0.0036ug.mL-1
IC50=17.4ug.mL-1
IC50=11.5ug.mL-1
IC50=17ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HT-29
External ID: CHEMBL3737328
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=78%
Activity=78%
Activity=74%
Activity=77%
Activity=67%
Activity=65%
Activity=59%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3737327
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014
Standard TypeStandard RelationStandard Value
Ratio IC50=0.4
Ratio IC50=0.7
Ratio IC50=0.2
Ratio IC50=1.1
Ratio IC50=0.3
Ratio IC50=6
Ratio IC50<0.1
Ratio IC50=1.1
Ratio IC50=2.2
Ratio IC50=5.7
Ratio IC50=0.3
Ratio IC50=1.5
Ratio IC50=0.9
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HT-29
External ID: CHEMBL3737456
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=57%
Activity=65%
Activity=81%
Activity=100%
Activity=100%
Activity=41%
Activity=59%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3737326
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014
Standard TypeStandard RelationStandard Value
Ratio IC50=0.2
Ratio IC50=2.6
Ratio IC50<0.1
Ratio IC50=0.9
Ratio IC50=1.1
Ratio IC50=6.5
Ratio IC50=0.2
Ratio IC50=0.8
Ratio IC50=1.7
Ratio IC50=3.4
Ratio IC50=0.2
Ratio IC50=1.6
Ratio IC50=0.1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HT-29
External ID: CHEMBL3737463
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 103
First Page: 488
Last Page: 496
DOI: 10.1016/j.ejmech.2015.09.014

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=51%
Activity=46%
Activity=74%
Activity=100%
Activity=100%
Activity=59%
Activity=100%