HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：tRNA (guanine-N(1)-)-methyltransferase

External ID: CHEMBL5252128

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2023
Volume: 90
First Page: 129331
Last Page: 129331
DOI: 10.1016/j.bmcl.2023.129331

Target ChEMBL ID: CHEMBL5291575
ChEMBL Target Name: tRNA (guanine-N(1)-)-methyltransferase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
160	IC50	=	160000	nM	Outside typical range
0.011	IC50	=	11	nM
13	IC50	=	13000	nM
48	IC50	=	48000	nM
1.3	IC50	=	1300	nM
10	IC50	>	10000	nM
3.2	IC50	=	3200	nM

145255-19-2 靶点实验数据