HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histone-arginine methyltransferase CARM1

External ID: CHEMBL5138963

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 17.0
First Page: 11574
Last Page: 11606
DOI: 10.1021/acs.jmedchem.2c00252

Target ChEMBL ID: CHEMBL5406
ChEMBL Target Name: Histone-arginine methyltransferase CARM1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.0759	Kd	=	75.9	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histone-arginine methyltransferase CARM1

External ID: CHEMBL5138964

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 17.0
First Page: 11574
Last Page: 11606
DOI: 10.1021/acs.jmedchem.2c00252

Target ChEMBL ID: CHEMBL5406
ChEMBL Target Name: Histone-arginine methyltransferase CARM1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
K	=	2.9	10^5/Ms
K	=	1.67	10^4/Ms

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histone-arginine methyltransferase CARM1

External ID: CHEMBL5138965

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 17.0
First Page: 11574
Last Page: 11606
DOI: 10.1021/acs.jmedchem.2c00252

Target ChEMBL ID: CHEMBL5406
ChEMBL Target Name: Histone-arginine methyltransferase CARM1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
K	=	0.003	1/s
K	=	0.011	1/s

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histone-arginine methyltransferase CARM1

External ID: CHEMBL5138966

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 17.0
First Page: 11574
Last Page: 11606
DOI: 10.1021/acs.jmedchem.2c00252

Target ChEMBL ID: CHEMBL5406
ChEMBL Target Name: Histone-arginine methyltransferase CARM1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
TIME	=	0.09258	hr
TIME	=	0.02525	hr

14031-35-7 靶点实验数据