HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Glutamate receptor ionotropic, NMDA 3A

External ID: CHEMBL749643

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 2
First Page: 260
Last Page: 267
DOI: 10.1021/jm00028a009

Target ChEMBL ID: CHEMBL1907608
ChEMBL Target Name: Glutamate NMDA receptor
ChEMBL Target Type: PROTEIN COMPLEX GROUP - Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor)
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.57	IC50	=	1570	nM
0.407	IC50	=	407	nM
3.45	IC50	=	3450	nM
10.3	IC50	=	10300	nM
10	IC50	=	10000	nM
1.6	IC50	=	1600	nM
1.1	IC50	=	1100	nM
0.33	IC50	=	330	nM
2	IC50	=	2000	nM
34	IC50	=	34000	nM
0.1	IC50	=	100	nM
0.069	IC50	=	69	nM
1.03	IC50	=	1030	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sigma non-opioid intracellular receptor 1

External ID: CHEMBL803935

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1994
Volume: 37
Issue: 2
First Page: 260
Last Page: 267
DOI: 10.1021/jm00028a009

Target ChEMBL ID: CHEMBL287
ChEMBL Target Name: Sigma opioid receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.059	IC50	=	59	nM
0.096	IC50	=	96	nM
0.397	IC50	=	397	nM
0.245	IC50	=	245	nM
8.11	IC50	=	8110	nM
1.99	IC50	=	1990	nM
0.125	IC50	=	125	nM
0.165	IC50	=	165	nM
0.042	IC50	=	42	nM
0.033	IC50	=	33	nM
1.21	IC50	=	1210	nM
10.7	IC50	=	10700	nM
2.9	IC50	=	2900	nM

137159-93-4 靶点实验数据