HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1B

External ID: CHEMBL615620

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 4
First Page: 859
Last Page: 863
DOI: 10.1021/jm00124a021

Target ChEMBL ID: CHEMBL3459
ChEMBL Target Name: Serotonin 1b (5-HT1b) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.8	Ki	=	1800	nM
10	Ki	>	10000	nM
10	Ki	>	10000	nM
1	Ki	=	1000	nM
1	Ki	=	1000	nM
10	Ki	>	10000	nM
0.017	Ki	=	17	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL616305

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 4
First Page: 859
Last Page: 863
DOI: 10.1021/jm00124a021

Target ChEMBL ID: CHEMBL273
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.039	Ki	=	39	nM
0.095	Ki	=	95	nM
0.08	Ki	=	80	nM
0.06	Ki	=	60	nM
3.3	Ki	=	3300	nM
25	Ki	>	25000	nM
0.4	Ki	=	400	nM
0.345	Ki	=	345	nM
4.9	Ki	=	4900	nM
0.055	Ki	=	55	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Beta-3 adrenergic receptor

External ID: CHEMBL652718

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 4
First Page: 859
Last Page: 863
DOI: 10.1021/jm00124a021

Target ChEMBL ID: CHEMBL2095166
ChEMBL Target Name: Adrenergic receptor beta
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Units	Activity Comment
Ki	nM	Not Determined
Ki	nM	Not Determined
Ki	nM	Not Determined
Ki	nM	Not Determined
Ki	nM	Not Determined
Ki	nM	Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1B

External ID: CHEMBL616539

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 26
First Page: 4415
Last Page: 4419
DOI: 10.1021/jm970507t

Target ChEMBL ID: CHEMBL1898
ChEMBL Target Name: Serotonin 1b (5-HT1b) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
5.96	Ki	=	5960	nM
1.205	Ki	=	1205	nM
2.675	Ki	=	2675	nM
1.225	Ki	=	1225	nM
7.66	Ki	=	7660	nM
1.12	Ki	=	1120	nM
0.094	Ki	=	94	nM
0.066	Ki	=	66	nM
0.1	Ki	=	100	nM
3.45	Ki	=	3450	nM
0.29	Ki	=	290	nM
10	Ki	>	10000	nM
0.47	Ki	=	470	nM
10	Ki	>	10000	nM

13658-95-2 靶点实验数据