HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prostaglandin E2 receptor EP3 subtype

External ID: CHEMBL764948

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2001
Volume: 11
Issue: 5
First Page: 747
Last Page: 749
DOI: 10.1016/s0960-894x(01)00056-7

Target ChEMBL ID: CHEMBL3710
ChEMBL Target Name: Prostanoid EP3 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Residual binding	=	25	%
Residual binding	=	8	%
Residual binding	=	5	%
Residual binding	=	91	%
Residual binding	=	77	%
Residual binding	=	74	%
Residual binding	=	48	%
Residual binding	=	61	%
Residual binding	=	54	%
Residual binding	=	84	%
Residual binding	=	100	%
Residual binding	=	27	%
Residual binding	=	84	%
Residual binding	=	96	%
Residual binding	=	55	%
Residual binding	=	89	%
Residual binding	=	93	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Beta-lactamase

External ID: CHEMBL649554

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 23
First Page: 4577
Last Page: 4586
DOI: 10.1021/jm980343w

Target ChEMBL ID: CHEMBL2026
ChEMBL Target Name: Beta-lactamase AmpC
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
7.3	Ki	=	7300	nM
10.5	Ki	=	10500	nM
100	Ki	>	100000	nM
0.027	Ki	=	27	nM
100	Ki	>	100000	nM
2.9	Ki	=	2900	nM
0.2	Ki	=	200	nM
5.9	Ki	=	5900	nM
100	Ki	>	100000	nM
10.9	Ki	=	10900	nM
53.4	Ki	=	53400	nM
7	Ki	=	7000	nM
5.4	Ki	=	5400	nM
100	Ki	>	100000	nM
22.1	Ki	=	22100	nM
2.5	Ki	=	2500	nM
0.5	Ki	=	500	nM
3.8	Ki	=	3800	nM
3	Ki	=	3000	nM
3.9	Ki	=	3900	nM

13331-23-2 靶点实验数据