HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1641185

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 12
First Page: 5767
Last Page: 5772
DOI: 10.1016/j.ejmech.2010.09.034

Standard Type	Standard Relation	Standard Value
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4
Ratio	>	4

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma cruzi

External ID: CHEMBL1641187

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 12
First Page: 5767
Last Page: 5772
DOI: 10.1016/j.ejmech.2010.09.034

Target ChEMBL ID: CHEMBL368
ChEMBL Target Name: Trypanosoma cruzi
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Active
Activity				Active
Activity				Active
GI	=	19.1	%
Activity				Active
Activity				Active
Activity				Active
Activity				Active
Activity				Active
Activity				Active
Activity				Active
Activity				Active
GI	=	25	%
GI	=	50	%
GI	=	0	%
Activity				Active
Activity				Active
Activity				Active
Activity				Active
Activity				Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Triosephosphate isomerase, glycosomal

External ID: CHEMBL1641189

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 12
First Page: 5767
Last Page: 5772
DOI: 10.1016/j.ejmech.2010.09.034

Target ChEMBL ID: CHEMBL5834
ChEMBL Target Name: Triosephosphate isomerase, glycosomal
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition	=	52	%
Inhibition	=	35	%
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition	=	69	%
Inhibition	=	45	%
Inhibition	=	98	%
Inhibition	=	17	%
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Triosephosphate isomerase, glycosomal

External ID: CHEMBL1641190

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 12
First Page: 5767
Last Page: 5772
DOI: 10.1016/j.ejmech.2010.09.034

Target ChEMBL ID: CHEMBL5834
ChEMBL Target Name: Triosephosphate isomerase, glycosomal
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	33	%
Inhibition	=	24	%
Inhibition	=	18	%
Inhibition	=	83	%
Inhibition	=	93	%
Inhibition	=	30	%
Inhibition	=	0	%
Inhibition	=	0	%
Inhibition	=	0	%
Inhibition	=	76	%
Inhibition	=	14	%
Inhibition	=	29	%
Inhibition	=	87	%
Inhibition	=	74	%
Inhibition	=	95	%
Inhibition	=	0	%
Inhibition	=	53	%
Inhibition	=	25	%
Inhibition	=	0	%
Inhibition	=	32	%

131981-75-4 靶点实验数据