HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Urease subunit beta

External ID: CHEMBL3595645

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2015
Volume: 23
Issue: 15
First Page: 4508
Last Page: 4513
DOI: 10.1016/j.bmc.2015.06.014

Target ChEMBL ID: CHEMBL3885651
ChEMBL Target Name: Urease subunit alpha/Urease subunit beta
ChEMBL Target Type: PROTEIN COMPLEX - Target is a defined protein complex, consisting of multiple subunits
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous protein complex subunits assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
1.92	IC50	=	1920	nM
28.1	IC50	=	28100	nM
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Urease subunit beta

External ID: CHEMBL3595644

Protocol: N/A

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.62	IC50	=	620	nM
8.26	IC50	=	8260	nM
64.9	IC50	=	64900	nM
45.1	IC50	=	45100	nM
238.7	IC50	=	238700	nM	Outside typical range
236.5	IC50	=	236500	nM	Outside typical range
410.3	IC50	=	410300	nM	Outside typical range

13159-84-7 靶点实验数据