HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histamine H2 receptor

External ID: CHEMBL693275

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1992
Volume: 35
Issue: 17
First Page: 3239
Last Page: 3246
DOI: 10.1021/jm00095a021

Target ChEMBL ID: CHEMBL2882
ChEMBL Target Name: Histamine H2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
Intrinsic activity	=	1
Intrinsic activity	=	1.06
Intrinsic activity	=	0.94
Intrinsic activity	=	0.96

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histamine H2 receptor

External ID: CHEMBL696490

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1992
Volume: 35
Issue: 17
First Page: 3239
Last Page: 3246
DOI: 10.1021/jm00095a021

Target ChEMBL ID: CHEMBL2882
ChEMBL Target Name: Histamine H2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
15.1356	Kd	=	15135.61	nM
173.78	Kd	=	173780.08	nM	Outside typical range
5.01187	Kd	=	5011.87	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histamine H2 receptor

External ID: CHEMBL693231

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1992
Volume: 35
Issue: 17
First Page: 3239
Last Page: 3246
DOI: 10.1021/jm00095a021

Target ChEMBL ID: CHEMBL2882
ChEMBL Target Name: Histamine H2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
pD2	=	6.14
pD2	=	5.67
pD2	=	7.8
pD2	=	4.6
pD2	=	4.7
pD2	=	7.7
pD2	=	4.67

124458-10-2 靶点实验数据