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123715-79-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Aromatase
External ID: CHEMBL5241253
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2020
Volume: 208
First Page: 112845
Last Page: 112845
DOI: 10.1016/j.ejmech.2020.112845

Target ChEMBL ID: CHEMBL1978
ChEMBL Target Name: Cytochrome P450 19A1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
2.39883IC50=2398.83nM
16.9824IC50=16982.44nM
26.0016IC50=26001.6nM
2.99916IC50=2999.16nM
2.30144IC50=2301.44nM
0.18281IC50=182.81nM
0.82985IC50=829.85nM
87.9022IC50=87902.25nM
1.49968IC50=1499.68nM
100.925IC50=100925.29nMOutside typical range
0.19011IC50=190.11nM
1.79887IC50=1798.87nM
0.22491IC50=224.91nM
3.59749IC50=3597.49nM
1IC50=1000nM
1.7338IC50=1733.8nM
1.1508IC50=1150.8nM
0.69984IC50=699.84nM
29.1072IC50=29107.17nM
0.05702IC50=57.02nM