HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL875200

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 3
First Page: 599
Last Page: 602
DOI: 10.1016/j.bmcl.2004.11.040

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
2.7	Ki	=	2700	nM
0.0108	Ki	=	10.8	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL829269

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 3
First Page: 599
Last Page: 602
DOI: 10.1016/j.bmcl.2004.11.040

Standard Type	Standard Relation	Standard Value
Ratio	=	33.1
Ratio	=	1.55

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL829666

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 3
First Page: 599
Last Page: 602
DOI: 10.1016/j.bmcl.2004.11.040

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.15	Ki	=	1150	nM
3.65	Ki	=	3650	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5127543

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 3.0
First Page: 1612
Last Page: 1661
DOI: 10.1021/acs.jmedchem.0c01915

Standard Type	Standard Relation	Standard Value	Standard Units
T1/2	>=	5	hr
T1/2	=	0.1367	hr
T1/2	>=	5	hr
T1/2	>=	5	hr

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5127544

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 3.0
First Page: 1612
Last Page: 1661
DOI: 10.1021/acs.jmedchem.0c01915

Standard Type	Standard Relation	Standard Value	Standard Units
T1/2	>=	5	hr
T1/2	>=	5	hr
T1/2	>=	5	hr

123715-02-6 靶点实验数据