HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Estrogen receptor beta

External ID: CHEMBL4371244

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2018
Volume: 61
Issue: 11
First Page: 4720
Last Page: 4738
DOI: 10.1021/acs.jmedchem.7b01601

Target ChEMBL ID: CHEMBL242
ChEMBL Target Name: Estrogen receptor beta
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
10	EC50	>	10000	nM
	EC50				Not Determined
	EC50				Not Determined
10	EC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Estrogen receptor beta

External ID: CHEMBL4371261

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2018
Volume: 61
Issue: 11
First Page: 4720
Last Page: 4738
DOI: 10.1021/acs.jmedchem.7b01601

Target ChEMBL ID: CHEMBL242
ChEMBL Target Name: Estrogen receptor beta
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
0.04	EC50	=	40	nM
	EC50				Not Determined
	EC50				Not Determined
0.101	EC50	=	101	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Estrogen receptor beta

External ID: CHEMBL4371245

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2018
Volume: 61
Issue: 11
First Page: 4720
Last Page: 4738
DOI: 10.1021/acs.jmedchem.7b01601

Target ChEMBL ID: CHEMBL242
ChEMBL Target Name: Estrogen receptor beta
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
21	EC50	=	21000	nM
0.012	EC50	=	12	nM
1.4	EC50	=	1400	nM
0.225	EC50	=	225	nM
0.066	EC50	=	66	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Estrogen receptor

External ID: CHEMBL4371262

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2018
Volume: 61
Issue: 11
First Page: 4720
Last Page: 4738
DOI: 10.1021/acs.jmedchem.7b01601

Target ChEMBL ID: CHEMBL206
ChEMBL Target Name: Estrogen receptor alpha
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
10	EC50	>	10000	nM
	EC50				Not Determined
	EC50				Not Determined
10	EC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Estrogen receptor

External ID: CHEMBL4371263

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2018
Volume: 61
Issue: 11
First Page: 4720
Last Page: 4738
DOI: 10.1021/acs.jmedchem.7b01601

Target ChEMBL ID: CHEMBL206
ChEMBL Target Name: Estrogen receptor alpha
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
10	EC50	>	10000	nM
	EC50				Not Determined
	EC50				Not Determined
10	EC50	>	10000	nM

1237147-89-5 靶点实验数据