HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_1833_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	Standard Relation	PubChem Standard Value	IC50 Qualifier	IC50	Target Accession(s)	Ligand	Target
IC50		0.55		550	P23458	BDBM103729	Tyrosine-protein kinase JAK1 [850-1154]
IC50	>	5	>	5000	P23458	BDBM103730	Tyrosine-protein kinase JAK1 [850-1154]
IC50	>	5	>	5000	P23458	BDBM103731	Tyrosine-protein kinase JAK1 [850-1154]
IC50	>	5	>	5000	P23458	BDBM103732	Tyrosine-protein kinase JAK1 [850-1154]
IC50		3		3000	P23458	BDBM103733	Tyrosine-protein kinase JAK1 [850-1154]
IC50		0.55		550	P23458	BDBM103734	Tyrosine-protein kinase JAK1 [850-1154]
IC50		0.55		550	P23458	BDBM103735	Tyrosine-protein kinase JAK1 [850-1154]
IC50	<	0.1	<	100	P23458	BDBM103736	Tyrosine-protein kinase JAK1 [850-1154]
IC50		0.55		550	P23458	BDBM348890	Tyrosine-protein kinase JAK1 [850-1154]

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_9885_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.291	291	P23458	BDBM103729	Tyrosine-protein kinase JAK1 [850-1154]
IC50	1.032	1032	P23458	BDBM103730	Tyrosine-protein kinase JAK1 [850-1154]
IC50	1.45	1450	P23458	BDBM103731	Tyrosine-protein kinase JAK1 [850-1154]
IC50	3.448	3448	P23458	BDBM103732	Tyrosine-protein kinase JAK1 [850-1154]
IC50	0.504	504	P23458	BDBM103733	Tyrosine-protein kinase JAK1 [850-1154]
IC50	0.435	435	P23458	BDBM103734	Tyrosine-protein kinase JAK1 [850-1154]
IC50	0.334	334	P23458	BDBM103735	Tyrosine-protein kinase JAK1 [850-1154]

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_5991_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.0501	50.1	P23458	BDBM103727	Tyrosine-protein kinase JAK1
IC50	0.04829	48.29	P23458	BDBM103727	Tyrosine-protein kinase JAK1
IC50	0.03137	31.37	O60674	BDBM103727	Tyrosine-protein kinase JAK2
IC50	0.04116	41.16	O60674	BDBM103727	Tyrosine-protein kinase JAK2
IC50	0.05549	55.49	O60674	BDBM103727	Tyrosine-protein kinase JAK2
IC50	0.16734	167.34	O60674	BDBM103727	Tyrosine-protein kinase JAK2
IC50	0.14935	149.35	P52333	BDBM103727	Tyrosine-protein kinase JAK3
IC50	0.1873	187.3	P52333	BDBM103727	Tyrosine-protein kinase JAK3
IC50	0.1893	189.3	P52333	BDBM103727	Tyrosine-protein kinase JAK3
IC50	0.1947	194.7	P52333	BDBM103727	Tyrosine-protein kinase JAK3
IC50	0.0727	72.7	P29597	BDBM103727	Non-receptor tyrosine-protein kinase TYK2
IC50	0.07375	73.75	P29597	BDBM103727	Non-receptor tyrosine-protein kinase TYK2
IC50	0.07907	79.07	P29597	BDBM103727	Non-receptor tyrosine-protein kinase TYK2
IC50	0.08677	86.77	P29597	BDBM103727	Non-receptor tyrosine-protein kinase TYK2
IC50	0.05091	50.91	P23458	BDBM103728	Tyrosine-protein kinase JAK1
IC50	0.05211	52.11	P23458	BDBM103728	Tyrosine-protein kinase JAK1
IC50	0.03873	38.73	O60674	BDBM103728	Tyrosine-protein kinase JAK2
IC50	0.1523	152.3	O60674	BDBM103728	Tyrosine-protein kinase JAK2
IC50	0.1847	184.7	O60674	BDBM103728	Tyrosine-protein kinase JAK2
IC50	2.843	2843	P52333	BDBM103728	Tyrosine-protein kinase JAK3

1206159-99-0 靶点实验数据