HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3280532

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 2
First Page: 233
Last Page: 236
DOI: 10.1021/jm00212a009

Standard Type	Standard Relation	Standard Value	Activity Comment
Inhibition_index	=	260
Inhibition_index			Not Determined
Inhibition_index	=	600
Inhibition_index	=	1000
Inhibition_index	=	600
Inhibition_index			Not Determined
Inhibition_index	=	800
Inhibition_index	=	53
Inhibition_index	=	120
Inhibition_index	=	800
Inhibition_index	=	450
Inhibition_index			Not Determined
Inhibition_index	=	400
Inhibition_index	=	210
Inhibition_index	=	180
Inhibition_index	=	105
Inhibition_index	=	76
Inhibition_index	=	250
Inhibition_index	=	700
Inhibition_index	=	600

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3280534

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 2
First Page: 233
Last Page: 236
DOI: 10.1021/jm00212a009

Standard Type	Standard Relation	Standard Value
pKa	=	4.58
pKa	=	2.5
pKa	=	2.75
pKa	=	5.1
pKa	=	2.24
pKa	=	2.46
pKa	=	3.6
pKa	=	2.5

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_8055_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	EC50	Target Accession(s)	Ligand	Target
EC50	1.9	1900	A0A0R4IM31	BDBM50339586	Olfactory receptor class A-like protein 1
EC50	199.9	199900	A0A0R4IM31	BDBM50339587	Olfactory receptor class A-like protein 1
EC50	22.8	22800	A0A0R4IM31	BDBM52946	Olfactory receptor class A-like protein 1
EC50	14.8	14800	A0A0R4IM31	BDBM231632	Olfactory receptor class A-like protein 1
EC50	16	16000	A0A0R4IM31	BDBM231633	Olfactory receptor class A-like protein 1
EC50	91.7	91700	A0A0R4IM31	BDBM231635	Olfactory receptor class A-like protein 1
EC50	191.8	191800	A0A0R4IM31	BDBM231636	Olfactory receptor class A-like protein 1
EC50	221	221000	A0A0R4IM31	BDBM231637	Olfactory receptor class A-like protein 1

1197-55-3 靶点实验数据