HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：B16

External ID: CHEMBL652824

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 12
First Page: 2181
Last Page: 2190
DOI: 10.1021/jm00395a004

Target ChEMBL ID: CHEMBL381
ChEMBL Target Name: B16
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
67	IC50	=	67000	nM
100	IC50	>	100000	nM
50	IC50	=	50000	nM
100	IC50	>	100000	nM
7	IC50	=	7000	nM
100	IC50	>	100000	nM
13	IC50	=	13000	nM
66	IC50	=	66000	nM
100	IC50	>	100000	nM
7	IC50	=	7000	nM
10	IC50	=	10000	nM
6	IC50	=	6000	nM
6	IC50	=	6000	nM
2	IC50	=	2000	nM
100	IC50	>	100000	nM
50	IC50	=	50000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL723207

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 12
First Page: 2181
Last Page: 2190
DOI: 10.1021/jm00395a004

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MTD	=	95	uM kg-1
MTD	=	60	uM kg-1
MTD	=	50	uM kg-1
MTD	=	60	uM kg-1
MTD	=	320	uM kg-1
MTD	=	300	uM kg-1
MTD	=	110	uM kg-1
MTD	=	670	uM kg-1
MTD	=	320	uM kg-1
MTD	=	120	uM kg-1
MTD	=	72	uM kg-1
MTD	>	600	uM kg-1
MTD	=	280	uM kg-1
MTD	=	18	uM kg-1
MTD	=	48	uM kg-1
MTD	=	82	uM kg-1
MTD	>	300	uM kg-1
MTD	=	1000	uM kg-1
MTD	=	17	uM kg-1
MTD	=	80	uM kg-1

1179-06-2 靶点实验数据