HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL616313

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1993
Volume: 36
Issue: 17
First Page: 2519
Last Page: 2525
DOI: 10.1021/jm00069a010

Target ChEMBL ID: CHEMBL273
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Units	Activity Comment
Ki	nM	Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2B

External ID: CHEMBL826008

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1993
Volume: 36
Issue: 17
First Page: 2519
Last Page: 2525
DOI: 10.1021/jm00069a010

Target ChEMBL ID: CHEMBL2093870
ChEMBL Target Name: Serotonin 2 (5-HT2) receptor
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value
Ratio	=	1000
Ratio	=	2100
Ratio	=	650
Ratio	>	70
Ratio	>	5
Ratio	=	85

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2C

External ID: CHEMBL616836

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1993
Volume: 36
Issue: 17
First Page: 2519
Last Page: 2525
DOI: 10.1021/jm00069a010

Target ChEMBL ID: CHEMBL324
ChEMBL Target Name: Serotonin 2c (5-HT2c) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3.2	Ki	=	3200	nM
10	Ki	>	10000	nM
10	Ki	>	10000	nM
3.3	Ki	=	3300	nM
100	Ki	>	100000	nM
10	Ki	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2B

External ID: CHEMBL617674

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1993
Volume: 36
Issue: 17
First Page: 2519
Last Page: 2525
DOI: 10.1021/jm00069a010

Target ChEMBL ID: CHEMBL2093870
ChEMBL Target Name: Serotonin 2 (5-HT2) receptor
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.005	Ki	=	5	nM
0.03	Ki	=	30	nM
0.6	Ki	=	600	nM
0.08	Ki	=	80	nM
100	Ki	>	100000	nM
0.295	Ki	=	295	nM

116753-54-9 靶点实验数据