HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Beta-glucosidase

External ID: CHEMBL832785

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL4192
ChEMBL Target Name: Beta-glucosidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
34	IC50	=	34000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sucrase-isomaltase, intestinal

External ID: CHEMBL832911

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL3114
ChEMBL Target Name: Sucrase-isomaltase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.31	IC50	=	310	nM
0.28	IC50	=	280	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sucrase-isomaltase, intestinal

External ID: CHEMBL827988

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL3114
ChEMBL Target Name: Sucrase-isomaltase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
1.2	IC50	=	1200	nM
0.66	IC50	=	660	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sucrase-isomaltase, intestinal

External ID: CHEMBL827987

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL3114
ChEMBL Target Name: Sucrase-isomaltase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
3.5	IC50	=	3500	nM
1.5	IC50	=	1500	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Putative alpha-glucosidase

External ID: CHEMBL826969

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL5280
ChEMBL Target Name: Alpha-glucosidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.08	IC50	=	80	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Beta-glucosidase A

External ID: CHEMBL835490

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2004
Volume: 14
Issue: 24
First Page: 5991
Last Page: 5995
DOI: 10.1016/j.bmcl.2004.09.086

Target ChEMBL ID: CHEMBL4622
ChEMBL Target Name: Beta-glucosidase A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	<	50	%

11075-17-5 靶点实验数据