前往化源商城

107-91-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Induced myeloid leukemia cell differentiation protein Mcl-1
External ID: CHEMBL2345533
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 59
First Page: 141
Last Page: 149
DOI: 10.1016/j.ejmech.2012.10.050

Target ChEMBL ID: CHEMBL4361
ChEMBL Target Name: Induced myeloid leukemia cell differentiation protein Mcl-1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
6.72Kd=6720nM
46.17Kd=46170nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Induced myeloid leukemia cell differentiation protein Mcl-1
External ID: CHEMBL2345532
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 59
First Page: 141
Last Page: 149
DOI: 10.1016/j.ejmech.2012.10.050

Target ChEMBL ID: CHEMBL4361
ChEMBL Target Name: Induced myeloid leukemia cell differentiation protein Mcl-1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
324.69Kd=324690nM
0.95499Kd=954.99nM
0.96Kd=960nM
1.8197Kd=1819.7nM
52.25Kd=52250nM
13.4896Kd=13489.63nM
13.52Kd=13520nM
1.44544Kd=1445.44nM
1.45Kd=1450nM
4.89779Kd=4897.79nM
1.58Kd=1580nM
0.15849Kd=158.49nM
0.16Kd=160nM
6.60693Kd=6606.93nM
1.07152Kd=1071.52nM
1.06Kd=1060nM
8.31764Kd=8317.64nM
8.27Kd=8270nM