HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sigma non-opioid intracellular receptor 1

External ID: CHEMBL804883

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 9
First Page: 2421
Last Page: 2429
DOI: 10.1021/jm00171a016

Target ChEMBL ID: CHEMBL287
ChEMBL Target Name: Sigma opioid receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.0083	IC50	=	8.3	nM
0.0588	IC50	=	58.8	nM
0.397	IC50	=	397	nM
0.0138	IC50	=	13.8	nM
1.2	IC50	=	1200	nM
7.15	IC50	=	7150	nM
0.935	IC50	=	935	nM
0.012	IC50	=	12	nM
0.271	IC50	=	271	nM
0.215	IC50	=	215	nM
0.006	IC50	=	6	nM
0.173	IC50	=	173	nM
0.036	IC50	=	36	nM
0.463	IC50	=	463	nM
0.75	IC50	=	750	nM
0.34	IC50	=	340	nM
0.54	IC50	=	540	nM
0.112	IC50	=	112	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sigma non-opioid intracellular receptor 1

External ID: CHEMBL873129

Protocol: N/A

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.016	IC50	=	16	nM
0.039	IC50	=	39	nM
0.044	IC50	=	44	nM
5.1	IC50	=	5100	nM
3.8	IC50	=	3800	nM
0.14	IC50	=	140	nM
0.766	IC50	=	766	nM
0.094	IC50	=	94	nM
0.032	IC50	=	32	nM
0.008	IC50	=	8	nM
0.237	IC50	=	237	nM
0.011	IC50	=	11	nM

106916-80-7 靶点实验数据