HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sodium- and chloride-dependent GABA transporter 1

External ID: CHEMBL4342201

Protocol: N/A

Comment: Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 13
First Page: 2753
Last Page: 2763
DOI: 10.1016/j.bmc.2019.05.001

Target ChEMBL ID: CHEMBL5445
ChEMBL Target Name: GABA transporter 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	57	%
Activity	=	48	%
Activity	=	79	%
Activity	=	79	%
Activity	=	79	%
Activity	=	87	%
Activity	=	65	%
Activity	=	81	%
Activity	=	59	%
Activity	=	59	%
Activity	=	85	%
Activity	=	79	%
Activity	=	59	%
Activity	=	20	%
Activity	=	59	%
Activity	=	36	%
Activity	=	65	%
Activity	=	65	%
Activity	=	79	%
Activity	=	55	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cytochrome P450 2A6

External ID: CHEMBL1924632

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2011
Volume: 19
Issue: 23
First Page: 7186
Last Page: 7193
DOI: 10.1016/j.bmc.2011.09.054

Target ChEMBL ID: CHEMBL5282
ChEMBL Target Name: Cytochrome P450 2A6
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.1	IC50	=	100	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
1.5	IC50	=	1500	nM
1.7	IC50	=	1700	nM
100	IC50	>	100000	nM

105-07-7 靶点实验数据