HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1

External ID: CHEMBL930181

Protocol: N/A

Comment: Journal: Nature
Year: 2007
Volume: 450
Issue: 7170
First Page: 712
Last Page: 716
DOI: 10.1038/nature06261

Target ChEMBL ID: CHEMBL4506
ChEMBL Target Name: NAD-dependent deacetylase sirtuin 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Activity Comment
Activity	Active
Activity	Active
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1

External ID: CHEMBL933821

Protocol: N/A

Comment: Journal: Nature
Year: 2007
Volume: 450
Issue: 7170
First Page: 712
Last Page: 716
DOI: 10.1038/nature06261

Target ChEMBL ID: CHEMBL4506
ChEMBL Target Name: NAD-dependent deacetylase sirtuin 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1

External ID: CHEMBL933817

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Nature
Year: 2007
Volume: 450
Issue: 7170
First Page: 712
Last Page: 716
DOI: 10.1038/nature06261

Target ChEMBL ID: CHEMBL4506
ChEMBL Target Name: NAD-dependent deacetylase sirtuin 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
	Activity	=	296	%
0.16	EC50	=	160	nM
	Activity	=	781	%
2.9	EC50	=	2900	nM
	Activity	=	447	%

1001908-89-9 靶点实验数据