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100-84-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Acetylcholinesterase
External ID: CHEMBL643382
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1992
Volume: 35
Issue: 3
First Page: 584
Last Page: 589
DOI: 10.1021/jm00081a022

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
4.9IC50=4900nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Acetylcholinesterase
External ID: CHEMBL648291
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1992
Volume: 35
Issue: 3
First Page: 584
Last Page: 589
DOI: 10.1021/jm00081a022

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.001995IC50=1.995nM
0.03981IC50=39.81nM
0.04571IC50=45.71nM
0.01IC50=10nM
0.03631IC50=36.31nM
0.003981IC50=3.981nM
0.001IC50=1nM
3.63078IC50=3630.78nM
0.21878IC50=218.78nM
0.1IC50=100nM
0.00955IC50=9.55nM
4.89779IC50=4897.79nM
0.00955IC50=9.55nM