78471-44-0

• 常用中文名：1-(4-氯苄基)哌啶-4-胺三氟乙酸酯
• 常用英文名：1-(4-CHLOROBENZYL)-1H-1,2,3,4-TETRAAZOL-5-YLAMINE
• CAS号：78471-44-0
• 分子式：C₁₄H₁₈ClF₃N₂O₂
• 分子量：338.75300
• 发布时间：2019-01-02 18:51:16
• 更新时间：2024-01-09 12:24:42

名称

• 中文名: 1-(4-氯苄基)哌啶-4-胺三氟乙酸酯
• 英文名: 1-[(4-chlorophenyl)methyl]piperidin-4-amine,2,2,2-trifluoroacetic acid

物化性质

• 密度: 1.15g/cm3
• 沸点: 311.6ºC at 760 mmHg
• 分子式: C₁₄H₁₈ClF₃N₂O₂
• 分子量: 338.75300
• 闪点: 142.2ºC
• 精确质量: 338.10100
• PSA: 66.56000
• LogP: 3.53460
• 折射率: 1.571

合成路线

1052528-90-1 ~57% 78471-44-0

文献：ASTRAZENECA AB Patent: WO2009/35407 A1, 2009 ; Location in patent: Page/Page column 10; 21 ;

1286275-72-6 ~% 78471-44-0

文献：Nguyen, Thuy; Sakasegawa, Yuji; Doh-Ura, Katsumi; Go, Mei-Lin European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2917 - 2929

241495-43-2 ~% 78471-44-0

文献：Shum; Peet; Weintraub; Le; Zhao; Barbone; Cashman; Tsay; Dwyer; Loos; Powers; Kropp; Wright; Bitonti; Dumont; Borcherding Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 4-7 p. 1067 - 1078

104-83-6 ~% 78471-44-0

文献：Shum; Peet; Weintraub; Le; Zhao; Barbone; Cashman; Tsay; Dwyer; Loos; Powers; Kropp; Wright; Bitonti; Dumont; Borcherding Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 4-7 p. 1067 - 1078

873-76-7 ~% 78471-44-0

文献：Nguyen, Thuy; Sakasegawa, Yuji; Doh-Ura, Katsumi; Go, Mei-Lin European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2917 - 2929

68726-76-1 ~83% 78471-44-0

文献：Moragues; Prieto; Spickett; Vega; Salazar; Roberts Farmaco, Edizione Scientifica, 1980 , vol. 35, # 11 p. 951 - 964

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