447406-78-2

• 常用中文名：索格列扎
• 常用英文名：2-[4-[[2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]-2-methylpropanoic acid
• CAS号：447406-78-2
• 分子式：C₂₃H₂₁F₄NO₃S₂
• 分子量：499.54100
• 发布时间：2018-09-16 18:53:28
• 更新时间：2025-08-24 20:40:17

名称

• 中文名: 索格列扎
• 英文名: 2-[4-[[2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]-2-methylpropanoic acid
• 中文别名: 2-[4-[[[2-[2-氟-4-(三氟甲基)苯基]-4-甲基-1,3-噻唑-5-基]甲基]硫基]-2-甲基苯氧基]-2-甲基丙酸
• 英文别名: Sodelglitazar

物化性质

• 密度: 1.4
• 分子式: C₂₃H₂₁F₄NO₃S₂
• 分子量: 499.54100
• 精确质量: 499.09000
• PSA: 112.96000
• LogP: 7.11910

合成路线

447406-50-0 57-15-8 ~72% 447406-78-2

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2003/74504 A2, 2003 ; Location in patent: Page/Page column 40-42 ;

447406-50-0 2052-01-9 ~81% 447406-78-2

文献：Brown, Andrew D.; Davis, Roman D.; Fitzgerald, Russ N.; Glover, Bobby N.; Harvey, Kim A.; Jones, Lynda A.; Liu, Bing; Patterson, Daniel E.; Sharp, Matthew J. Organic Process Research and Development, 2009 , vol. 13, # 2 p. 297 - 302

447406-77-1 317319-36-1 ~% 447406-78-2

文献：Brown, Andrew D.; Davis, Roman D.; Fitzgerald, Russ N.; Glover, Bobby N.; Harvey, Kim A.; Jones, Lynda A.; Liu, Bing; Patterson, Daniel E.; Sharp, Matthew J. Organic Process Research and Development, 2009 , vol. 13, # 2 p. 297 - 302