139264-15-6

• 常用中文名：二甲基佐米曲普坦
• 常用英文名：4-[[3-(2-aminoethyl)-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
• CAS号：139264-15-6
• 分子式：C₁₄H₁₇N₃O₂
• 分子量：259.30400
• 发布时间：2016-03-31 11:25:45
• 更新时间：2024-01-23 15:57:31

名称

• 中文名: 二甲基佐米曲普坦
• 英文名: 4-[[3-(2-aminoethyl)-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
• 英文别名: 2-Oxazolidinone,4-[[3-(2-aminoethyl)-1H-indol-5-yl]methyl]-,(S); 4-[3-(2-Aminoethyl)-1H-indol-5-yl]methyl-2-oxazolidinone; Didesmethyl Zolmitriptan (); (S)-2-[5-[(2-oxo-1,3-oxazolidin-4-yl)methyl]-1H-indol-3-yl]ethanamine; (S)-2-<5-<(2-oxo-1,3-oxazolidin-4-yl)methyl>-1H-indol-3-yl>ethylamine; (4S)-4-[3-(2-aminoethyl)-1H-5-indolylmethyl]-1,3-oxazolan-2-one

物化性质

• 密度: 1.299g/cm3
• 沸点: 595ºC at 760 mmHg
• 分子式: C₁₄H₁₇N₃O₂
• 分子量: 259.30400
• 闪点: 313.6ºC
• 精确质量: 259.13200
• PSA: 83.63000
• LogP: 1.66030
• 蒸汽压: 4E-14mmHg at 25°C
• 折射率: 1.657

合成路线

868622-21-3 ~42% 139264-15-6

文献：Aminul, Islam; Chandan, Bhar; Sahadev, Katam Patent: US2005/245585 A1, 2005 ; Location in patent: Page/Page column 9 ;

6346-09-4 187975-62-8 ~59% 139264-15-6

文献：Mittapelli, Vasantha; Ray, Puma Chandra; Chauhan, Yogendra Kumar; Datta, Debashish Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 4 p. 590 - 594

949-99-5 ~% 139264-15-6

文献：Journal of Medicinal Chemistry, , vol. 38, # 18 p. 3566 - 3580

89288-22-2 ~% 139264-15-6

文献：Journal of Medicinal Chemistry, , vol. 38, # 18 p. 3566 - 3580

17193-40-7 ~% 139264-15-6

文献：Journal of Medicinal Chemistry, , vol. 38, # 18 p. 3566 - 3580

139264-55-4 ~% 139264-15-6

文献：Journal of Medicinal Chemistry, , vol. 38, # 18 p. 3566 - 3580

868622-25-7 ~% 139264-15-6

文献：US2005/245585 A1, ; Page/Page column title page; Figure 1 ;

上下游产品

上游产品  7
868622-21-3 6346-09-4 949-99-5 89288-22-2
17193-40-7 139264-55-4 868622-25-7
下游产品  1
139264-17-8