188813-16-3

• 常用中文名：8-bromo-6-chlorochromen-2-one
• 常用英文名：8-bromo-6-chlorochromen-2-one
• CAS号：188813-16-3
• 分子式：C₉H₄BrClO₂
• 分子量：259.48400
• 发布时间：2017-05-25 23:59:46
• 更新时间：2025-09-12 20:58:03

名称

• 英文名: 8-bromo-6-chlorochromen-2-one
• 英文别名: 8-bromo-6-chloro-2H-1-benzopyran-2-one; 8-bromo-6-chloro-chromen-2-one; 2H-1-Benzopyran-2-one,8-bromo-6-chloro; 8-bromo-6-chloro-2H-chromen-2-one

物化性质

• 分子式: C₉H₄BrClO₂
• 分子量: 259.48400
• 精确质量: 257.90800
• PSA: 30.21000
• LogP: 3.20890

合成路线

952657-01-1 ~94% 188813-16-3

文献：GLAXO GROUP LIMITED Patent: WO2007/118130 A2, 2007 ; Location in patent: Page/Page column 27 ;

19652-32-5 4279-77-0 ~90% 188813-16-3

文献：Wei, Jia; Wang, Pengcheng; Jia, Qianfa; Huang, Jiaoyao; Du, Zhiyun; Zhang, Kun; Wang, Jian European Journal of Organic Chemistry, 2013 , # 21 p. 4499 - 4502

19652-32-5 108-24-7 ~76% 188813-16-3

文献：Clark, Jerry D.; Weisenburger, Gerald A.; Keith Anderson; Colson, Pierre-Jean; Edney, Albert D.; Gallagher, Donald J.; Peter Kleine; Knable, Carl M.; Lantz, Melissa K.; Moore, Christine M. V.; Murphy, James B.; Rogers, Thomas E.; Ruminski, Peter G.; Shah, Ajit S.; Storer, Neil; Wise, Bruce E. Organic Process Research and Development, 2004 , vol. 8, # 1 p. 51 - 61

19652-32-5 ~% 188813-16-3

文献：Nagarajan, Srinivasan R.; Devadas, Balekudru; Malecha, James W.; Lu, Hwang-Fun; Ruminski, Peter G.; Rico, Joseph G.; Rogers, Thomas E.; Marrufo, Laura D.; Collins, Joe T.; Kleine, H. Peter; Lantz, Melissa K.; Zhu, Jun; Green, Nawasa F.; Russell, Mark A.; Landis, Bryan H.; Miller, Lawrence M.; Meyer, Debra M.; Duffin, Tiffany D.; Engleman, V. Wayne; Finn, Mary B.; Freeman, Sandra K.; Griggs, David W.; Williams, Melanie L.; Nickols, Maureen A.; Pegg, Jodi A.; Shannon, Kristen E.; Steininger, Christina; Westlin, Marisa M.; Nickols, G. Alan; Keene, Jeffery L. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 11 p. 3783 - 3800