221141-87-3

• 常用中文名：56 反式-(1-苄基-4-苯基吡咯烷基-3-基)甲醇
• 常用英文名：1-Benzyl-4-phenyl-3-pyrrolidinemethanol
• CAS号：221141-87-3
• 分子式：C₁₈H₂₁NO
• 分子量：267.36500
• 发布时间：2018-12-06 00:32:56
• 更新时间：2025-09-10 16:23:04

名称

• 中文名: 1-苄基-4-苯基-3-吡咯烷甲醇
• 英文名: (1-benzyl-4-phenylpyrrolidin-3-yl)methanol
• 英文别名: [(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol; 3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-,(3R,4S); 1-Benzyl-4-phenyl-3-pyrrolidinemethanol; 1-benzyl-3-(R)-hydroxymethyl-4-(S)-phenylpyrrolidine

物化性质

• 密度: 1.11g/cm3
• 沸点: 389.7ºC at 760mmHg
• 分子式: C₁₈H₂₁NO
• 分子量: 267.36500
• 闪点: 181.3ºC
• 精确质量: 267.16200
• PSA: 23.47000
• LogP: 2.83240
• 外观性状: 白色固体
• 蒸汽压: 8.99E-07mmHg at 25°C
• 折射率: 1.595
• 储存条件: 2-8℃

合成路线

1201574-92-6 ~97% 221141-87-3

文献：ASTELLAS PHARMA INC. Patent: US2012/22271 A1, 2012 ; Location in patent: Page/Page column 9 ;

189498-44-0 ~55% 221141-87-3

文献：Kong, Laval Chan Chun; Moinet, Christophe; Vaillancourt, Louis; Bubenik, Monica Patent: US2006/14769 A1, 2006 ; Location in patent: Page/Page column 14 ;

221141-86-2 ~68% 221141-87-3

文献：Hale, Jeffrey J.; Budhu, Richard J.; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Siciliano, Salvatore; Gould, Sandra L.; DeMartino, Julie A.; Springer, Martin S. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 11 p. 1437 - 1440

93102-05-7 ~% 221141-87-3

文献：Hale, Jeffrey J.; Budhu, Richard J.; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Siciliano, Salvatore; Gould, Sandra L.; DeMartino, Julie A.; Springer, Martin S. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 11 p. 1437 - 1440

20780-53-4 ~% 221141-87-3

文献：ASTELLAS PHARMA INC. Patent: US2012/22271 A1, 2012 ;

706-03-6 ~% 221141-87-3

文献：ASTELLAS PHARMA INC. Patent: US2012/22271 A1, 2012 ;

128891-66-7 ~% 221141-87-3

文献：Hale, Jeffrey J.; Budhu, Richard J.; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Siciliano, Salvatore; Gould, Sandra L.; DeMartino, Julie A.; Springer, Martin S. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 11 p. 1437 - 1440

上下游产品

上游产品  5
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706-03-6
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