141025-16-3

• 常用中文名：N,N'-Bis(2-bromoethyl)phosphorodiamidic acid
• 常用英文名：N,N'-Bis(2-bromoethyl)phosphorodiamidic acid
• CAS号：141025-16-3
• 分子式：C₄H₁₁Br₂N₂O₂P
• 分子量：309.92400
• 发布时间：2016-07-07 08:21:37
• 更新时间：2025-09-17 12:02:28

名称

• 英文名: bis(2-bromoethylamino)phosphinic acid
• 英文别名: N,N'-Bis(2-bromoethyl)phosphoric acid diamide; Phosphorodiamidic acid,N,N'-bis(2-bromoethyl); HO-P(=O)(NHCH2CH2Br)2; bromoifosfamide mustard; Dibromo isophoramide mustard; N,N'-Bis(2-bromoethyl)phosphorodiamidic acid

物化性质

• 密度: 1.934g/cm3
• 沸点: 370.2ºC at 760mmHg
• 分子式: C₄H₁₁Br₂N₂O₂P
• 分子量: 309.92400
• 闪点: 177.7ºC
• 精确质量: 307.89200
• PSA: 71.17000
• LogP: 1.83760
• 蒸汽压: 1.69E-06mmHg at 25°C
• 折射率: 1.557

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TD2516500 CHEMICAL NAME : Phosphorodiamidic acid, N,N'-bis(2-bromoethyl)- CAS REGISTRY NUMBER : 141025-16-3 LAST UPDATED : 199212 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C4-H11-Br2-N2-O2-P MOLECULAR WEIGHT : 309.96 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Human HeLa cell DOSE/DURATION : 800 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 43,937,1992

合成路线

2576-47-8 ~% 141025-16-3

文献：THRESHOLD PHARMACEUTICALS, INC. Patent: WO2007/2931 A2, 2007 ; Location in patent: Page/Page column 125-126 ;

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