360-63-4

• 常用中文名：9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(hydrogen phosphonate)
• 常用英文名：9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(hydrogen phosphonate)
• CAS号：360-63-4
• 分子式：C₂₂H₃₀FO₈P
• 分子量：472.44100
• 发布时间：2017-05-27 06:20:54
• 更新时间：2023-10-16 20:23:53

名称

• 英文名: (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4 -dien-21-yl dihydrogen phosphate
• 英文别名: dexamethasone-21-phosphate; Dexamethasone phosphate; Dexamethasone-21-dihydrogen-phosphate; Betnelan phosphate; Neodecadron; Wymesone; Oradexon phosphate; Dexamethasone 21-orthophosphate; Hexadrol phosphate

物化性质

• 密度: 1.45g/cm3
• 沸点: 669.6ºC at 760mmHg
• 分子式: C₂₂H₃₀FO₈P
• 分子量: 472.44100
• 闪点: 358.7ºC
• 精确质量: 472.16600
• PSA: 151.17000
• LogP: 2.01270
• 折射率: 1.594

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU4055500 CHEMICAL NAME : Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 21-(dihydrogen phosphate) CAS REGISTRY NUMBER : 360-63-4 LAST UPDATED : 198612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H30-F-O8-P HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 21,587,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 21,587,1966