6860-12-4

• 常用中文名：TNY
• 常用英文名：TNY
• CAS号：6860-12-4
• 分子式：C₉H₁₄Cl₃N₃O₂
• 分子量：302.58500
• 发布时间：2017-07-20 14:01:32
• 更新时间：2024-01-09 09:12:03

名称

• 英文名: 5-[bis(2-chloroethyl)aminomethyl]-1H-pyrimidine-2,4-dione,hydrochloride
• 英文别名: Thyminalkamine; Thyminalkylamine; KC 433; Uracil,5-((bis(2-chloroethyl)amino)methyl)-,hydrochloride; TNY; Uracil,hydrochloride; Ypenyl; 5-((bis(2-chloroethyl)amino)methyl)uracil hydrochloride

物化性质

• 密度: 1.331g/cm3
• 沸点: 348.7ºC at 760mmHg
• 分子式: C₉H₁₄Cl₃N₃O₂
• 分子量: 302.58500
• 闪点: 164.7ºC
• 精确质量: 301.01500
• PSA: 68.96000
• LogP: 1.14480
• 折射率: 1.528

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV9013070 CHEMICAL NAME : 2,4(1H,3H)-Pyrimidinedione, 5-((bis(2-chloroethyl)amino)methyl)-, monohydrochloride CAS REGISTRY NUMBER : 6860-12-4 LAST UPDATED : 199304 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H13-Cl2-N3-O2.Cl-H MOLECULAR WEIGHT : 302.61 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3100 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 32,1649,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 15,455,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 12,87,1965

合成路线

50-00-0 334-22-5 66-22-8 ~35% 6860-12-4

文献：Istanbullu, Hueseyin; Zupko, Istvan; Alptuezuen, Vildan; Erciyas, Ercin Turkish Journal of Chemistry, 2012 , vol. 36, # 4 p. 583 - 592

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