2441-88-5

• 常用中文名：Benzenemethanol, a-[(2-pyrimidinylamino)methyl]-,hydrochloride (1:1)
• 常用英文名：Benzenemethanol, a-[(2-pyrimidinylamino)methyl]-,hydrochloride (1:1)
• CAS号：2441-88-5
• 分子式：C₁₂H₁₄ClN₃O
• 分子量：251.71200
• 发布时间：2016-12-03 22:55:57
• 更新时间：2023-01-16 14:06:56

名称

• 英文名: 1-phenyl-2-(pyrimidin-2-ylamino)ethanol,hydrochloride
• 英文别名: Fenyripol hydrochloride; IN 836; Fenyripol HCl

物化性质

• 密度: 1.26g/cm3
• 沸点: 429.7ºC at 760mmHg
• 分子式: C₁₂H₁₄ClN₃O
• 分子量: 251.71200
• 闪点: 213.7ºC
• 精确质量: 251.08300
• PSA: 58.04000
• LogP: 2.49710

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DP1230000 CHEMICAL NAME : Benzyl alcohol, alpha-((2-pyrimidinylamino)methyl)-, monohydrochloride CAS REGISTRY NUMBER : 2441-88-5 LAST UPDATED : 199503 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C12-H13-N3-O.Cl-H MOLECULAR WEIGHT : 251.74 WISWESSER LINE NOTATION : T6N CNJ BM1YQR &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 235 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 850 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 360 mg/kg TOXIC EFFECTS : Behavioral - coma Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Behavioral - coma Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965