14297-87-1

• 常用中文名：3-O-苄吗啉
• 常用英文名：(4R,4aR,7S,7aR,12bS)-3-methyl-9-phenylmethoxy-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol
• CAS号：14297-87-1
• 分子式：C₂₄H₂₅NO₃
• 分子量：375.46000
• 发布时间：2018-05-18 08:00:00
• 更新时间：2024-01-12 15:56:56

名称

• 中文名: 3-O-苄吗啉
• 英文名: (4R,4aR,7S,7aR,12bS)-3-methyl-9-phenylmethoxy-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol
• 英文别名: 3-benzylmorphine; (-)-3-O-benzylmorphine; O3-Benzylmorphine; benzylmorphine; 3-Benzyloxy-4,5alpha-epoxy-17-methyl-7-morphinen-6alpha-ol; Morphine,benzyl

物化性质

• 密度: 1.33g/cm3
• 沸点: 552.5ºC at 760 mmHg
• 分子式: C₂₄H₂₅NO₃
• 分子量: 375.46000
• 闪点: 287.9ºC
• 精确质量: 375.18300
• PSA: 52.93000
• LogP: 2.72680
• 蒸汽压: 4.85E-13mmHg at 25°C
• 折射率: 1.689

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QD0710000 CHEMICAL NAME : Morphinan-6-alpha-ol, 3-(benzyloxy)-7,8-didehydro-4,5-alpha-epoxy-17-methyl - CAS REGISTRY NUMBER : 14297-87-1 LAST UPDATED : 199106 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C24-H25-N-O3 MOLECULAR WEIGHT : 375.50 WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FQ JO1R& P1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,8,1938

合成路线

52-26-6 100-44-7 ~74% 14297-87-1

文献：Brands; Lie; Maat Recueil des Travaux Chimiques des Pays Bas, 1986 , vol. 105, # 12 p. 544 - 548

100-44-7 57-27-2 ~% 14297-87-1

文献：Merck E. Merck's Jahresberichte, 1898 , p. 20 Archiv der Pharmazie (Weinheim, Germany), 1899 , vol. 237, p. 220 Full Text Show Details Merck Patent: DE91813 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 1245

57-27-2 ~% 14297-87-1

文献：Rodionow Bulletin de la Societe Chimique de France, 1929 , vol. <4>45, p. 116

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100-44-7 57-27-2