35155-28-3

• 常用中文名：10α-甲氧基-1-甲基-d3-9,10-二氢麦角酚
• 常用英文名：10-methoxy-1,6-dimethylergoline-8beta-methanol
• CAS号：35155-28-3
• 分子式：C₁₈H₂₄N₂O₂
• 分子量：300.39500
• 发布时间：2016-12-09 20:13:09
• 更新时间：2026-09-10 21:08:30

名称

• 中文名: 10α-甲氧基-1-甲基-d3-9,10-二氢麦角酚
• 英文名: [(8β,10ξ)-10-Methoxy-1,6-dimethylergolin-8-yl]methanol
• 中文别名: 尼麦角林杂质H二盐酸; 甲基化的光麦角醇(尼麦角林中间体三); N-甲基光麦角醇; 尼麦角林杂质3(尼麦角林杂质C); 尼麦角林杂质C; 10ALPHA-甲氧基-1-甲基二氢麦角醇; 尼麦角林杂质05; 光麦角醇; 10A-甲氧基-1-甲基-9,10-二氢麦角醇; 1-甲基-10Α-甲氧基光麦角醇; 尼麦角林N-1; ((6,9R,10AS)-10A-甲氧基-4,7-二甲基-4,6,6A,7,8,9,10,10A-八氢吲哚[4,3-FG]喹啉-9-基)甲醇 (尼麦角林杂质); 尼麦角林中间体; 尼麦角林杂质3; (8Β)-10-甲氧基-1,6-二甲基麦角灵-8-甲醇; [(6,9R,10aS)-10a-甲氧基-4,7-二甲基-4,6,6a,7,8,9,10,10a-八氢吲哚[4,3-fg]喹啉-9-基]甲醇
• 英文别名: Nicergoline Intermediate N-1; Nicergoline Impurity C; 1-Methyl-10alpha-methoxydihydrolysergol; 1-Methyl-10a-methoxydihydrolysergol; 10a-Methoxy-1-methyl-9,10-dihydrolysergol; Hexadecen-(10c)-saeure-(1); 10Alpha-Methoxy-1-methyl-9,10-dihydrolysergol; Nicergoline Impurity H DiHCl; Nicergoline Impurity 3; ((6,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol; Nicergoline Impurity 5; Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8β); 10alpha-Methoxy-1-methyldihydrolysergol; Ergoline-8-methanol,10-methoxy-1,6-dimethyl-, (8b); [(6,9R,10aS)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl]methanol; 10Z-hexadecenoic acid; 1-Methyl-10alpha-methoxy-9,10-dihydrolysergol; ((6,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity); 10α-Methoxy-1-methyl-9,10-dihydrolysergol-D3; 10-Hexadecenoic acid,(10Z); cis-Hexadecen-(10)-saeure; Nicergoline intermediates; 10-Methoxy-1,6-dimethylergoline-8β-methanol; N-3 to API; Nicergoline Impurity 3(Nicergoline Impurity C); 10α-Methoxy-1-methyl-9,10-dihydrolysergol; Nergoline impurity C; Light ergotol; Methyl 10-Methoxy-6-methylergoline-8β-cboxylic acid; 10alpha-Methoxy-1-methyl-9,10-dihydrolysergol-D4; Methoxy-dimethylergoline-methanol; Meluol; (8β,10ξ)-10-Methoxy-1,6-dimethylergolin-8-yl]methanol

物化性质

• 密度: 1.27g/cm3
• 沸点: 459.8ºC at 760mmHg
• 分子式: C₁₈H₂₄N₂O₂
• 分子量: 300.39500
• 闪点: 231.9ºC
• 精确质量: 300.18400
• PSA: 37.63000
• LogP: 1.82660
• 折射率: 1.642

合成路线

27848-84-6 ~92% 20826-04-4 35155-28-3

文献：Gabor; Hamilton; Pittner Journal of Pharmaceutical Sciences, 1995 , vol. 84, # 9 p. 1120 - 1125