76351-84-3

• 常用中文名：2-Amino-N-(8-(p-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide
• 常用英文名：2-Amino-N-(8-(p-chlorobenzyl)-3-beta-nortropanyl)-4-methoxy-5-pyrimidi necarboxamide
• CAS号：76351-84-3
• 分子式：C₂₀H₂₄ClN₅O₂
• 分子量：401.89000
• 发布时间：2017-02-10 18:48:48
• 更新时间：2024-01-11 16:36:43

名称

• 英文名: 2-amino-N-[8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]-4-methoxypyrimidine-5-carboxamide

物化性质

• 密度: 1.36g/cm3
• 分子式: C₂₀H₂₄ClN₅O₂
• 分子量: 401.89000
• 精确质量: 401.16200
• PSA: 97.59000
• LogP: 3.08900
• 折射率: 1.648

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV7701270 CHEMICAL NAME : 5-Pyrimidinecarboxamide, 2-amino-N-(8-(p-chlorobenzyl)-3-beta-nortropanyl)-4-m ethoxy- CAS REGISTRY NUMBER : 76351-84-3 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H24-Cl-N5-O2 MOLECULAR WEIGHT : 401.94 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 220 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 19,105,1984

合成路线

104-83-6 76352-25-5 ~69% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

542-05-2 ~% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

532-24-1 ~% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

76272-36-1 ~% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

1515-26-0 ~% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

76352-24-4 ~% 76351-84-3

文献：Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110