72962-09-5

• 常用中文名：2-Amino-5-chloro-6-phenyl-4(1H)-pyrimidinone
• 常用英文名：2-Amino-5-chloro-6-phenyl-4(1H)-pyrimidinone
• CAS号：72962-09-5
• 分子式：C₁₀H₈ClN₃O
• 分子量：221.64300
• 发布时间：2017-03-20 05:36:05
• 更新时间：2025-09-19 12:21:17

名称

• 英文名: 2-amino-5-chloro-6-phenyl-1H-pyrimidin-4-one
• 英文别名: u-55,523

物化性质

• 密度: 1.48g/cm3
• 沸点: 375.1ºC at 760 mmHg
• 分子式: C₁₀H₈ClN₃O
• 分子量: 221.64300
• 闪点: 180.6ºC
• 精确质量: 221.03600
• PSA: 72.76000
• LogP: 2.01490
• 折射率: 1.688

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UW7352500 CHEMICAL NAME : 4(1H)-Pyrimidinone, 2-amino-5-chloro-6-phenyl- CAS REGISTRY NUMBER : 72962-09-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H8-Cl-N3-O MOLECULAR WEIGHT : 221.66 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 400 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 252,229,1991

合成路线

56741-94-7 ~45% 72962-09-5

文献：Evenaes, Johan; Edfeldt, Fredrik; Lepistoe, Matti; Svitacheva, Naila; Synnergren, Anna; Lundquist, Britta; Graense, Mia; Roennholm, Anna; Varga, Mikael; Wright, John; Wei, Min; Yue, Sherrie; Wang, Junfeng; Li, Chong; Li, Xuan; Chen, Gang; Liao, Yong; Lv, Gang; Tjoernebo, Ann; Narjes, Frank Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1315 - 1321

94-02-0 ~% 72962-09-5

文献：Skulnick; Weed; Eidson; Renis; Wierenga; Stringfellow Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1864 - 1869

98-88-4 ~% 72962-09-5

文献：Wierenga; Skulnick; Stringfellow; Weed; Renis; Eidson Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 237 - 239

614-27-7 ~% 72962-09-5

文献：Evenaes, Johan; Edfeldt, Fredrik; Lepistoe, Matti; Svitacheva, Naila; Synnergren, Anna; Lundquist, Britta; Graense, Mia; Roennholm, Anna; Varga, Mikael; Wright, John; Wei, Min; Yue, Sherrie; Wang, Junfeng; Li, Chong; Li, Xuan; Chen, Gang; Liao, Yong; Lv, Gang; Tjoernebo, Ann; Narjes, Frank Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1315 - 1321

93-58-3 ~% 72962-09-5

文献：Evenaes, Johan; Edfeldt, Fredrik; Lepistoe, Matti; Svitacheva, Naila; Synnergren, Anna; Lundquist, Britta; Graense, Mia; Roennholm, Anna; Varga, Mikael; Wright, John; Wei, Min; Yue, Sherrie; Wang, Junfeng; Li, Chong; Li, Xuan; Chen, Gang; Liao, Yong; Lv, Gang; Tjoernebo, Ann; Narjes, Frank Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1315 - 1321